Report A fifth of cancer therapy trials fail to enlist enough participants

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"Such trials represent a waste of scarce human and economic resources and contribute little to medical knowledge," note researchers, who have developed a mathematical tool to predict how difficult it might be to attract trial participants depending on a range of trial-specific factors.

The team, from the University of Washington and the Fred Hutchinson Cancer Research Center, both in Seattle, WA, writes about the new mathematical tool or algorithm - and how they arrived at it - in the Journal of the National Cancer Institute.

To develop the algorithm, the team first trawled through trials published in the last few years and identified several trial-related "risk factors" that are linked to low patient accrual rates.

They found, for instance, that trials requiring patients to give a tissue sample or undergo biopsy to decide if they can enroll tend to find it harder to attract participants than those that do not have such invasive eligibility tests.

Read more here. (Medical News Today)
 
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