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One dose of a new treatment, delivered by nasal spray, clears away build-ups of the toxic tau protein associated with Alzheimer’s disease from inside brain cells, improving memory, according to new research. It paves the way for new treatments for the debilitating disease.
A few years ago, abnormal clumps of tau proteins in the brain were found to be associated with Alzheimer’s disease. Since then, researchers have been working on a way of eradicating these toxic tangles, which have become a hallmark of the degenerative disease.
Now, researchers from the University of Texas Medical Branch (UTMB) have developed a breakthrough nasal spray containing antibodies that selectively target and clear away tau tangles, helping to restore cognitive function.
“This nasal spray approach opens new avenues for non-invasive delivery of tau therapeutic antibodies directly to the brain, and it holds promise for many neurogenerative diseases,” said Dr. Rakez Kayed, professor at the Department of Neurology at UTMB and the study’s corresponding author. “Our research highlights the potential of nasal tau immunotherapy to effectively target intracellular tau aggregates – a primary driver of neurodegeneration and cognitive decline in diseases like Alzheimer’s and other tauopathies.”
newatlas.com
A few years ago, abnormal clumps of tau proteins in the brain were found to be associated with Alzheimer’s disease. Since then, researchers have been working on a way of eradicating these toxic tangles, which have become a hallmark of the degenerative disease.
Now, researchers from the University of Texas Medical Branch (UTMB) have developed a breakthrough nasal spray containing antibodies that selectively target and clear away tau tangles, helping to restore cognitive function.
“This nasal spray approach opens new avenues for non-invasive delivery of tau therapeutic antibodies directly to the brain, and it holds promise for many neurogenerative diseases,” said Dr. Rakez Kayed, professor at the Department of Neurology at UTMB and the study’s corresponding author. “Our research highlights the potential of nasal tau immunotherapy to effectively target intracellular tau aggregates – a primary driver of neurodegeneration and cognitive decline in diseases like Alzheimer’s and other tauopathies.”
One-dose nasal spray clears toxic Alzheimer's proteins to improve memory
One dose of a new treatment, delivered by nasal spray, clears away build-ups of the toxic tau protein associated with Alzheimer’s disease from inside brain cells, improving memory, according to new research. It paves the way for new treatments for the debilitating disease.
newatlas.com
