Science Sound waves convert stem cells into bone in regenerative breakthrough

tom_mai78101

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Regrowing or replacing bone lost to disease is tricky and often painful. In a new study Australian researchers have found a relatively simple way to induce stem cells to turn into bone cells quickly and efficiently, using high-frequency sound waves.

Stem cells have enormous medical potential in helping to regenerate various tissues in the body, but bone has proven particularly hard to work with. Bone originates from what are known as mesenchymal stem cells (MSCs), which mostly reside in the bone marrow. Collecting these is a painful procedure, then converting them into bone cells is difficult to scale up to useful levels.

But researchers from RMIT have now found a faster and simpler way to induce MSCs to turn into bone cells. Previous studies have suggested that the vibrations from sound waves can induce cell differentiation, but it typically took over a week with mixed results. These experiments have been limited to low frequencies, and it was thought that higher frequencies would have little benefit. So for the new study, the RMIT team investigated these higher frequencies.

The team used a microchip that produced sound waves in the MHz range, and directed it at MSCs in silicon oil on a culture plate. They found the optimal setup was to expose these cells to 10-MHz signals for 10 minutes a day for five days, which boosted the levels of certain markers that indicated they were converting into bone cells.

 

The Helper

Necromancy Power over 9000
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10 years from I will be bumping this thread going what happened with this? Just saying....
 
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  • tom_mai78101 tom_mai78101:
    I dunno if I ever mentioned it here, but my bot actually helped someone discover a new way to clip through walls.
  • tom_mai78101 tom_mai78101:
    However, not many folks heard about it, because it's currently only compatible with the latest dev builds of multi-system emulator, BizHawk.
  • jonas jonas:
    cool! do you have a video?
  • tom_mai78101 tom_mai78101:
    I have a GIF though
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    In the GIF, I've configured it so the lower the "Main Value" is, the better. I had to compress it pretty far down though.
  • tom_mai78101 tom_mai78101:
    And this is the thread with the video that shows the wall clip. https://tasvideos.org/Forum/Topics/23453
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  • tom_mai78101 tom_mai78101:
    Hmm, about the Headline News, I noticed threads are being moved into the subforum (Health News, Environmental News, etc.). When that happens, the TH Forum Home page loses the articles, and instead would show old articles posted 1 or 2 weeks ago.
  • tom_mai78101 tom_mai78101:
    What do we do with the Home page?
  • Ghan Ghan:
    I added those forums to the filter for that widget.
  • tom_mai78101 tom_mai78101:
    Oh nice. They're back. Thanks.
  • tom_mai78101 tom_mai78101:
    Now I think it makes more sense for me to put news in their own subforums, without worry.
  • The Helper The Helper:
    Awesome Ghan thanks! I was purposely not moving the first 15 news articles in Headline news to the different subforums but I guess I don't have to do that now?
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    Question: Is there a way to remove thread redirects? It creates a copy of the moved thread and takes up space, and I am leaning towards wanting to remove them in the Headline News. But if they have an expiration date, I guess I'm fine with it.
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    If you move a thread please leave a permanent redirect. You can delete any redirects after 6 months. The redirects are left to help Search Engines find the moved content.
  • tom_mai78101 tom_mai78101:
    What if you move the permanent redirect, not the thread?
  • The Helper The Helper:
    I think that works but I have not messed with it. You can delete redirects though if you have to that will not delete the original thread
  • The Helper The Helper:
    if a redirect ends up in the same forum as the post it goes to though I think the redirect drops or fails or something but they are not bugged out and when you are working on an indirect the original post is safe.
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    Happy Early Friday :)
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    Fun Friday for me
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