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Scientists from the University of Birmingham found that suppressing the inflammatory response in the spinal cord may minimize damage following spinal cord injury.
Their findings, recently published in Clinical and Translational Medicine, show that AZD1236, an AstraZeneca medicine, may considerably reduce ‘secondary damage’ produced by the body’s response to spinal cord injury (SCI).
Animal models were used by researchers led by Professor Zubair Ahmed, Professor of Neuroscience and Section Lead for the Neuroscience and Ophthalmology Section at The University’s Institute of Inflammation and Ageing, to demonstrate that AZD1236 can promote significant nerve regeneration, with a dramatic 80% preservation in nerve function following spinal cord compression injury.
Crucially, this translated into an 85% improvement in movement and sensation. These dramatic effects were observed following only three days of treatment with AZD1236, starting within 24 hours post-injury. Within three weeks, the AZD1236 treated animals showed unprecedented recovery, while controls still showed significant deficits at six weeks post-injury.
Their findings, recently published in Clinical and Translational Medicine, show that AZD1236, an AstraZeneca medicine, may considerably reduce ‘secondary damage’ produced by the body’s response to spinal cord injury (SCI).
Animal models were used by researchers led by Professor Zubair Ahmed, Professor of Neuroscience and Section Lead for the Neuroscience and Ophthalmology Section at The University’s Institute of Inflammation and Ageing, to demonstrate that AZD1236 can promote significant nerve regeneration, with a dramatic 80% preservation in nerve function following spinal cord compression injury.
Crucially, this translated into an 85% improvement in movement and sensation. These dramatic effects were observed following only three days of treatment with AZD1236, starting within 24 hours post-injury. Within three weeks, the AZD1236 treated animals showed unprecedented recovery, while controls still showed significant deficits at six weeks post-injury.
Unprecedented Recovery: Drug Helps Treat Spinal Cord Injuries
New hope for spinal cord injury treatment Scientists from the University of Birmingham found that suppressing the inflammatory response in the spinal cord may minimize damage following spinal cord injury. Their findings, recently published in Clinical and Translational Medicine, show that AZD123
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