Health Warning: Popular Vitamin Supplement Causes Cancer Risk and Brain Metastasis

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University of Missouri researchers made the discovery while using bioluminescent imaging technology to study how nicotinamide riboside supplements work inside the body.

Commercial dietary supplements like nicotinamide riboside (NR), a form of vitamin B3, were linked to benefits related to cardiovascular, metabolic, and neurological health in previous studies. However, new research from the University of Missouri (MU) has found NR could actually increase the risk of serious disease, including developing cancer.

Scientists discovered that high levels of NR could not only increase someone’s risk of developing triple-negative breast cancer, but also could cause the cancer to metastasize or spread to the brain. The international team of researchers was led by Elena Goun, an associate professor of chemistry at MU and the corresponding author on the study. She said that once the cancer reaches the brain, the results are deadly because no viable treatment options exist at this time.

“Some people take them [vitamins and supplements] because they automatically assume that vitamins and supplements only have positive health benefits, but very little is known about how they actually work,” Goun said. “Because of this lack of knowledge, we were inspired to study the basic questions surrounding how vitamins and supplements work in the body.”

 
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