Health Why cannabis smells skunky

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As cannabis is legalized in more areas, it has become increasingly popular as a medicinal and recreational drug. This plant produces a pungent, skunk-like odor that is pleasing to some but repulsive to others. Now, researchers reporting in ACS Omega have discovered a new family of prenylated volatile sulfur compounds (VSCs) that give cannabis its characteristic skunky aroma. The findings open up opportunities to investigate the molecules for medicinal benefits, the researchers say.

Cannabis sativa L. produces more than 200 known aroma compounds. Prior studies have focused mainly on terpenoids—molecules that range in odor from fuel-like to woody, citrusy or floral. Different cannabis cultivars have diverse mixtures of these compounds that contribute to their unique aromas. However, although terpenoids are the most abundant aroma compounds in cannabis, there is little evidence that they provide the underlying skunk-like smell of many cultivars. Skunks use several VSCs in their smelly defense sprays, so Iain Oswald and colleagues suspected that there could be similar molecules in cannabis. The team decided to use sensitive analytical techniques to find out.

 
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