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Blockbuster weight loss and diabetes drugs like Wegovy and Ozempic may be associated with an increased risk of three rare, but severe, stomach conditions in non-diabetic patients, according to a new epidemiological study released Thursday.
The study, published in the research journal JAMA, comes as Novo Nordisk’s Wegovy, Ozempic and similar treatments skyrocket in popularity in the U.S. for their ability to cause dramatic weight loss over time. But those drugs, known as GLP-1s, are also facing increased scrutiny after some patients reported experiencing stomach paralysis and suicidal ideation while taking them.
GLP-1s work by slowing digestion to suppress a person’s appetite but can cause problems if that process slows down too much.
Researchers at the University of British Columbia said the conditions in the study include one disorder not named in the warning labels for those drugs: stomach paralysis, which slows or completely stops the movement of food from the stomach to the intestine and can cause symptoms like persistent vomiting.
www.cnbc.com
The study, published in the research journal JAMA, comes as Novo Nordisk’s Wegovy, Ozempic and similar treatments skyrocket in popularity in the U.S. for their ability to cause dramatic weight loss over time. But those drugs, known as GLP-1s, are also facing increased scrutiny after some patients reported experiencing stomach paralysis and suicidal ideation while taking them.
GLP-1s work by slowing digestion to suppress a person’s appetite but can cause problems if that process slows down too much.
Researchers at the University of British Columbia said the conditions in the study include one disorder not named in the warning labels for those drugs: stomach paralysis, which slows or completely stops the movement of food from the stomach to the intestine and can cause symptoms like persistent vomiting.
Weight loss drugs may be linked to stomach paralysis, other rare but severe issues, study says
The study comes as Novo Nordisk's Wegovy, Ozempic and similar treatments skyrocket in popularity in the U.S. for causing dramatic weight loss over time.
