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Imagine a pill that could instantly sober you up no matter how much you've had to drink, or a hangover cure that worked minutes after swallowing it. Hardened drinkers rejoice: researchers are about to begin human trials on an "alcohol antidote" that may soon offer a cure to alcoholism, reports New Scientist.
The drug is a chemical called dihydromyricetin, or DHM, and is derived from a Chinese variety of the oriental raisin tree, which has been used for at least 500 years in China as an effective hangover cure. So far the extract has only been tested on boozing rats, but with promising results.
"DHM will reduce the degree of drunkenness for the amount of alcohol drunk and will definitely reduce the hangover symptoms," said Jing Liang, lead researcher in the study. "In time, it will reduce [an alcoholic's] desire for alcohol."
Liang first tested how well DHM alleviated drunken rats' clumsiness and loss of coordination by measuring how long it took them to right themselves after being laid on their backs. Rats were injected with an alcohol equivalent of a human drinking 15 to 20 beers in two hours to ensure that they were sufficiently wasted. As one would expect, it took the rats about 70 minutes just to get back up on their feet. After a milligram of DHM (per kilogram of rat body weight) was added to the mixture, however, the rats were able to right themselves in just five minutes.
The drug is a chemical called dihydromyricetin, or DHM, and is derived from a Chinese variety of the oriental raisin tree, which has been used for at least 500 years in China as an effective hangover cure. So far the extract has only been tested on boozing rats, but with promising results.
"DHM will reduce the degree of drunkenness for the amount of alcohol drunk and will definitely reduce the hangover symptoms," said Jing Liang, lead researcher in the study. "In time, it will reduce [an alcoholic's] desire for alcohol."
Liang first tested how well DHM alleviated drunken rats' clumsiness and loss of coordination by measuring how long it took them to right themselves after being laid on their backs. Rats were injected with an alcohol equivalent of a human drinking 15 to 20 beers in two hours to ensure that they were sufficiently wasted. As one would expect, it took the rats about 70 minutes just to get back up on their feet. After a milligram of DHM (per kilogram of rat body weight) was added to the mixture, however, the rats were able to right themselves in just five minutes.
Chinese tree extract stops rats getting drunk
Ancient hangover cure could help problem drinkers stay sober, avoid hangovers and eventually kick the habit
www.newscientist.com
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