Health Reversal Of Alzheimer's Symptoms Within Minutes In Human Study

The Helper

Necromancy Power over 9000
Staff member
Reaction score
1,656
An extraordinary new scientific study, which for the first time documents marked improvement in Alzheimer’s disease within minutes of administration of a therapeutic molecule, has just been published in the Journal of Neuroinflammation.

This new study highlights the importance of certain soluble proteins, called cytokines, in Alzheimer’s disease. The study focuses on one of these cytokines, tumor necrosis factor-alpha(TNF), a critical component of the brain’s immune system. Normally, TNF finely regulates the transmission of neural impulses in the brain. The authors hypothesized that elevated levels of TNF in Alzheimer’s disease interfere with this regulation. To reduce elevated TNF, the authors gave patients an injection of an anti-TNF therapeutic called etanercept. Excess TNF-alpha has been documented in the cerebrospinal fluid of patients with Alzheimer’s.

 
Last edited:

tom_mai78101

The Helper Connoisseur / Ex-MineCraft Host
Staff member
Reaction score
1,458
Update to this news.



Pfizer Knew Its Drug Could Prevent Alzheimer’s. They Did Nothing About It, Says Post


In 2015, drug manufacturer Pfizer discovered that their drug Enbrel (etanercept), an anti-inflammatory used to treat rheumatoid arthritis, appeared to lower the risk of Alzheimer’s disease by a whopping 64 percent. No one ever learned about this discovery, however, because the company chose not to pursue any further investigation and decided not to release the findings. This comes from an investigative report released on Tuesday by The Washington Post.

Pfizer uncovered Enbrel’s potential for preventing Alzheimer’s during an analysis of hundreds of thousands insurance claims. Company documents obtained by The Washington Post state, “Enbrel could potentially safely prevent, treat and slow progression of Alzheimer’s disease.’’ However, figuring out if the drug would actually have that effect in people at risk of the disease would require an $80 million clinical trial.

After three years of internal debate, Pfizer decided against the trial, despite recommendations from researchers in the company’s division of inflammation and immunology. They also decided to keep their findings mum.

The company’s official stance today is that clinical trials weren’t likely to succeed because the molecules of the drug are too large to reach the brain. And the decision not to release their finding? Pfizer didn’t want to send outside researchers down a dead-end path.

This raises ethical questions about whether Pfizer had a responsibility to release this information to the scientific community. Alzheimer’s is, after all, a disease with at least 500,000 new diagnoses a year. While some experts say, yes, they absolutely should release those findings, others in the field of healthcare ethics claim that disclosures should be limited to information from clinical trials.


The following article explains the design flaws of Dr. Edward Tobinick's study (mentioned in OP) in detail, and it is likely why Pfizer didn't pursue a clinical trial:

 
Last edited:
General chit-chat
Help Users
  • No one is chatting at the moment.
  • The Helper The Helper:
    Chile was a photographer but they are long gone from the site and doing other stuff now
  • Varine Varine:
    Well one of them is like six months, and I think his other daughter is like five or six? Like, young enough he shouldn't have drugs around anyway.
    +1
  • Varine Varine:
    So my side business is doing home archives, like digitizing and restoring old photographs and negatives, so I'm looking for like a DSLR that can do good macro photos
  • Varine Varine:
    I have some special scanners for slides and negatives, but they are kind of limited when it comes to some types of film, so I'm thinking I can set up a kind of projection system and just use a good camera to capture some of them if I need to.
  • Varine Varine:
    So I'm just looking for recommendations, because I'd like to not spend more than like 800 dollars if I don't have to, which seems to be lower midrange for DSLR. Should I bother with something like that, or just wait and plan on spending a lot more?
  • Varine Varine:
    I know I need at least 24 megapixel because I need to be able to capture the film grain because that's kind of a thing I advertise about, and my admittedly very fast math and a guy on Reddit told me that's what I need
  • Varine Varine:
    I know a lot about film, I don't know shit about digital cameras
  • Varine Varine:
    I'll also probably need to set up a server at some point because these scans take up a huge amount of space. I'll worry about that when I have an office though
  • The Helper The Helper:
    I am sure Ghan could give you some solid advice on the Server stuff
  • The Helper The Helper:
    I hear that the latest IPhones and Samsungs have some of the best cameras out there.
  • jonas jonas:
    phone cameras are good for sending pics on whatsapp, but no good for macro photography
  • jonas jonas:
    I think you should buy a used macro lens, do you already have a system camera?
  • Varine Varine:
    No, I'm still looking into them and kind of leaning towards a Rebel T7 at the moment because it's pretty cheap and lenses seem pretty easy to come by. Used ones are only like 3-400 dollars, which is much cheaper than I was planning
  • jonas jonas:
    I can't really recommend you any specific lens or body due to lack of knowledge, but in my experience camera shops are very helpful, especially those that also sell used parts
  • Varine Varine:
    There's only one camera shop in my town and they seem to specialize in film, but I have time before I need it. I'm not in a rush so I'll keep researching them
  • jonas jonas:
    I think since you have such specific needs, you should find a way to give a try for different systems without having to commit to one
  • jonas jonas:
    It would suck to spend 400$ on a system that doesn't have the capability you need
  • jonas jonas:
    and it will probably take a couple of tries to get the settings right
  • Varine Varine:
    It would but I can also just make sure I can return them. The system I have works, it's pretty straightforward and I tested it with a camera I have. All it really is is a little cartridge that holds the transparency film and a white light source behind it that projects the image into the lens
  • Varine Varine:
    I'll have to fuck with the light a bit and try some different lighting methods to get color accuracy, but I have IT8 targets for that
    +1
  • The Helper The Helper:
    get that color accuracy :)
  • Varine Varine:
    They're really helpful for calibrating things because I'm really colorblind, so I'm not great at doing it by eye
    +2

    The Helper Discord

    Staff online

    Members online

    Affiliates

    Hive Workshop NUON Dome World Editor Tutorials

    Network Sponsors

    Apex Steel Pipe - Buys and sells Steel Pipe.
    Top