Health High blood caffeine levels may reduce body weight and type 2 diabetes risk


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A new study, published in BMJ Medicine, has looked at the effect of higher blood caffeine levels on body weight and the long-term risks of type 2 diabetes and major cardiovascular diseases, such as coronary artery disease, stroke, heart failure, and irregular heart rhythm (atrial fibrillation).

Researchers used a statistical technique called Mendelian randomization, which uses genetic variants as a tool to investigate the causal relationship between a trait and an outcome.

The results of their analysis showed that higher genetically predicted blood caffeine levels were associated with lower body weight (BMI). Higher genetically predicted blood caffeine levels were also associated with a lower risk of type 2 diabetes.

The findings suggest that it may be worth exploring the potential for calorie-free caffeinated drinks to play a role in lowering the risk of obesity and type 2 diabetes.

Dr Dipender Gill, senior author for the study, from Imperial College London’s School of Public Health, said: “These findings offer important insight into the potential causal effect of caffeine on adiposity [obesity] and diabetes risk. However, further clinical study is warranted before individuals should use these results to guide their dietary preferences.”

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