Health Intermittent Fasting Seems to Result in Dynamic Changes to The Human Brain

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Scientists looking to tackle our ongoing obesity crisis have made an important discovery: Intermittent fasting leads to significant changes both in the gut and the brain, which may open up new options for maintaining a healthy weight.

Researchers from China studied 25 volunteers classed as obese over a period of 62 days, during which they took part in an intermittent energy restriction (IER) program – a regime that involves careful control of calorie intake and fasting on some days.

Not only did the participants in the study lose weight – 7.6 kilograms (16.8 pounds) or 7.8 percent of their body weight on average – there was also evidence of shifts in the activity of obesity-related regions of the brain, and in the make-up of gut bacteria.

"Here we show that an IER diet changes the human brain-gut-microbiome axis," says health researcher Qiang Zeng from the Second Medical Center and National Clinical Research Center for Geriatric Diseases in China.

 
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