You cant really prohibit units from picking up certain items, but what you can do is force the unit to drop the item immediately.
You write a trigger which checks for (event) "unit aquired item" or something along those lines. You use a condition which compares the type of the item to the item type you want to limit. You also check the units type.
If the item was picked up by an inappropriate unit type you force the unit to drop the item. There is an action in the "Hero" category which does that.
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Most legit traffic is tracked on multiple Analytics and we have Cloud Flare setup to block a ton of stuff but still there is large amount of bots that seem to escape detection and show up in the user list of the forum. I have been watching this bullshit for a year and still cannot figure it out it is drving me crazy lol.