Science Newly-discovered human organ may help explain how cancer spreads

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A newly discovered network of fluid-filled channels in the human body may be a previously-unknown organ, and it seems to help transport cancer cells around the body.

This discovery was made by chance, from routine endoscopies – a procedure that involves inserting a thin camera into a person’s gastrointestinal tract. Newer approaches enable doctors to use this procedure to get a microscopic look at the tissue inside a person’s gut at the same time, with some surprising results.

One team had expected to find that the bile duct is surrounded by a hard, dense wall of tissue. But instead, they saw weird, unexplained patterns. They took their findings to Neil Theise, a pathologist at New York University School of Medicine.

When Theise used the same endomicroscopy device to look under the skin of his own nose, he saw a similar result. Further investigation of other organs suggested that these patterns are made by a type of fluid moving through channels that are everywhere in the body.

Theise reckons that every tissue in the body may be surrounded by a network of these channels, which essentially form an organ. The team estimate that the organ contains around a fifth of the total fluid volume of the human body. “We think they act as shock absorbers,” says Theise.

 
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